Analysis of inhaled allergen spectrum of children with allergic rhinitis in Guangzhou / 临床耳鼻咽喉头颈外科杂志

ABSTRACT

OBJECTIVE@#To explore the inhaled allergen distribution of children with allergic rhinitis in Guangzhou area and to analyze the relevant factors.@*METHOD@#Six hundred and twenty-six cases children in Guangzhou region diagnosed with allergic rhinitis from January 2009 to December 2011 in our outpatient department were tested with skin prick test (SPT). Ten of standardized common inhaled allergens were analysed. The variety of allergens positive rate was calculated. And the gender, age, living environment,history of asthma, eczema, history and family history of clinical data were analyzed.@*RESULT@#The positive rate of SPT was 84.82% (531/626). The dust mites(76.36%) and the house dust mite(72.84%) have the highest positive rate, then the positive rate of the dog hair (11.98%), cat hair (7.03%) and Blattella germanica (4.31%) was degressively. The positive rate was significantly correlated with family history, history of eczema and asthma. The positive rate was correlated with the gender, independent of the living environment. The intensity of the test has no significant correlation with gender, and was significantly correlated with other factors. The positive rate of SPT has significant difference in ages and the highest positive rate of SPT was in the 10-14 age group, the SPT rate was 93.8%. Three groups have significant differences in the positive rate of mite, dog hair and cat hair.@*CONCLUSION@#The main inhaled allergen in children with allergic rhinitis in Guangzhou area tested by SPT was mite, dog hair and cat hair, respectively. The different ages, living environment, family history, history of eczema and allergic rhinitis children with asthma were related with the pathogenesis and development of AR in childhood. Our results have the contribution to early diagnosis and intervention of children with allergic rhinitis in Guangzhou area.