The expression of FasL and ICAM-1 on the HEVs in the hypertrophic tonsils / 临床耳鼻咽喉头颈外科杂志
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
; (24): 700-702, 2007.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-748359
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE@#To investigate the expression of FasL and ICAM-1 on the HEVs in the hypertrophic tonsils and its clinical significance.@*METHOD@#Under the light microscopy, HE and immunohistochemistry methods were used to show the morphology of HEVs, the number of T, B lymphocytes, the expression intensity of FasL and ICAM-1 in 17 patients with the idiopathic tonsillar hypertrophy (ITH) and in 20 patients with the chronic hypertrophic tonsillitis (CHT).@*RESULT@#The expression intensity of ICAM-1 on the tonsillar HEVs in ITH group was significantly lower than that in CTH group (P < 0.05), but the intensity of FasL in ITH group was significantly higher than that in CHT group (P < 0.05).@*CONCLUSION@#FasL and ICAM-1 expression in the tonsillar HEVs contribute to the CHT and ITH. The former mainly makes IHT developed, and the latter promotes the process of the inflammation.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Patologia
/
Tonsila Palatina
/
Vênulas
/
Linfócitos B
/
Linfócitos T
/
Tonsilite
/
Molécula 1 de Adesão Intercelular
/
Endotélio
/
Alergia e Imunologia
/
Proteína Ligante Fas
Limite:
Adolescente
/
Criança
/
Criança, pré-escolar
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Clinical Otorhinolaryngology Head and Neck Surgery
Ano de publicação:
2007
Tipo de documento:
Artigo