Effect of histone deacetylase and its inhibitor on tumor / 国际肿瘤学杂志
Journal of International Oncology
; (12): 235-238, 2019.
Article
em Zh
| WPRIM
| ID: wpr-751697
Biblioteca responsável:
WPRO
ABSTRACT
The occurrence and progress of tumor is the result of the interaction of heredity and epigenetics. Histone deacetylation modification,as an important epigenetic modification,plays an important role in tumorigenesis and development. The abnormal expression of histone deacetylase in normal tissues and cells promotes the development of tumor and is related to the proliferation and apoptosis,angiogenesis,metastasis and drug resistance of tumor cells,and becomes a new target of tumor therapy. Histone deacetylase inhibitors as anti-tumor drugs have a good prospect of application.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of International Oncology
Ano de publicação:
2019
Tipo de documento:
Article