Establishment of a critical segmental bone defect model in a rabbit ulna / 中国基层医药

ABSTRACT

Objective To establish a critical segmental bone defect model in a rabbit ulna.Methods Twenty male New Zealand white rabbits were randomly assigned into 5 groups according to the digital table,and then 14,15,16,17 and 18mm segmental defects (contained periosteum) were created in the middle part of ulna on both sides,respectively.At 6 and 12 weeks after surgery,the repair of segmental bone defects was evaluated by na ked eyes,X-ray and histological examination.Results At 12 weeks after surgery,all of the segmental defects with the length of 14 and 15mm were completely repaired.But none of the defects with the length of 16,17 and 18mm was repaired.Conclusion The length of critical segmental bone defect in rabbit ulna was 16 mm.