Incidence of tuberculosis in Korean diabetics: Comparison with that in non-diabetic hypertensive subjects / 대한내과학회지
Korean Journal of Medicine
; : 646-651, 2010.
Article
em Ko
| WPRIM
| ID: wpr-75595
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND/AIMS: Tuberculosis remains a major cause of mortality in South Korea, and the prevalence of diabetes is also increasing rapidly. Diabetes is a well known risk factor for tuberculosis. However, the risk varies according to race and regional prevalence. We assessed the potential impact of diabetes as a risk factor for tuberculosis in South Korea. METHODS: We performed a retrospective cohort study in a secondary referral hospital. The incidence of tuberculosis in a diabetic cohort was compared with that in a non-diabetic hypertensive cohort for 6 years. Diabetics who visited our diabetic clinic and non-diabetic hypertensive patients who visited our cardiology clinic from Jan 2004 to April 2004 were assigned to the diabetic cohort and the non-diabetic hypertensive cohort, respectively. Patients in each cohort had to receive medications to control their diseases. Patients with end-stage renal disease, malignancy, or HIV infection were excluded. Relative risk and tuberculosis-free survival rates of each cohort were calculated. RESULTS: The incidences of tuberculosis were 32 in the diabetic cohort (n=2491; mean age, 59.1+/-11.8 years; 44.5% male) and ten in the non-diabetic hypertensive cohort (n=1885; mean age, 59.9+/-12.8 years; 41.6% male). The estimated annual incidences per 100,000 persons were 282.8 and 112.9, respectively. The relative risk was 2.220 (p=0.028; 95% confidence interval, 1.090~4.523). However, no significant difference in cumulative tuberculosis-free survival rate was observed between the cohorts (p=0.075). CONCLUSIONS: A trend for a higher incidence of tuberculosis existed in diabetics, as compared to non-diabetic hypertensive patients, among a Korean population.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Encaminhamento e Consulta
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Tuberculose
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Cardiologia
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Infecções por HIV
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Incidência
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Prevalência
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Taxa de Sobrevida
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Estudos Retrospectivos
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Fatores de Risco
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Estudos de Coortes
Tipo de estudo:
Etiology_studies
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Incidence_studies
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Observational_studies
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Prevalence_studies
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Prognostic_studies
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Risk_factors_studies
Limite:
Humans
País/Região como assunto:
Asia
Idioma:
Ko
Revista:
Korean Journal of Medicine
Ano de publicação:
2010
Tipo de documento:
Article