Multiple Eruptive Dermatofibromas in a Patient with Myasthenia Gravis Treated with Systemic Corticosteroid / 대한피부과학회지
Korean Journal of Dermatology
; : 194-196, 2019.
Article
em Ko
| WPRIM
| ID: wpr-759712
Biblioteca responsável:
WPRO
ABSTRACT
Dermatofibroma is a fibrohistiocytic tumor of the skin that commonly occurs as a solitary lesion on the lower extremities of young women. Multiple eruptive dermatofibromas (MEDFs), defined as the presence of 5 to 8 dermatofibromas appearing within a period of 4 months, are rare, and the etiology of MEDFs remains unknown. However, MEDFs are frequently thought to be associated with altered immunity, such as autoimmune diseases and immunosuppression. It is unclear why MEDFs occur in association with these conditions, but this relationship may suggest that MEDFs are the result of an abortive immunoreactive process. We herein describe a middle-aged woman who developed multiple dermatofibroma. She had myasthenia gravis for 8 years, and developed MEDFs after undergoing oral corticosteroid treatment (245 mg/week) for 3 months. Therefore, our case suggests that the use of immunosuppressants is a more dominant factor for the development of MEDFs than underlying autoimmune diseases.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Pele
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Doenças Autoimunes
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Terapia de Imunossupressão
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Histiocitoma Fibroso Benigno
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Extremidade Inferior
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Imunossupressores
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Miastenia Gravis
Limite:
Female
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Humans
Idioma:
Ko
Revista:
Korean Journal of Dermatology
Ano de publicação:
2019
Tipo de documento:
Article