Application of the Threshold of Toxicological Concern (TTC) to Biological Evaluation of Medical Devices / 中国医疗器械杂志
Chinese Journal of Medical Instrumentation
; (6): 282-285, 2019.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-772506
Biblioteca responsável:
WPRO
ABSTRACT
The threshold of toxicological concern (TTC), a risk estimation method based on compound structurally-related toxicity data, has been widely used by many countries and regions for the safety risk assessment of food packaging materials and additives etc. Toxicological risk estimation is of importance in the biological evaluation of medical devices. Application of the TTC approach to leachable from medical devices may reduce or replace some unnecessary biocompatibility tests, but consideration should be taken for contact duration and route differences, which could affect the applicability of TTC. We herein focused on analyzing the eligibility of TTC for its further application in biological evaluation of medical devices.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Padrões de Referência
/
Embalagem de Alimentos
/
Medição de Risco
/
Equipamentos e Provisões
/
Fenômenos Toxicológicos
Tipo de estudo:
Estudo de etiologia
/
Fatores de risco
Idioma:
Chinês
Revista:
Chinese Journal of Medical Instrumentation
Ano de publicação:
2019
Tipo de documento:
Artigo