Application of laparoscopy-assisted total gastrectomy in elderly patients ≥65 years with gastric cancer / 中华胃肠外科杂志
Chinese Journal of Gastrointestinal Surgery
; (12): 1396-1402, 2018.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-774442
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE@#To evaluate the safety and feasibility of laparoscopy-assisted total gastrectomy in gastric cancer patients over 65 years old.@*METHODS@#Clinical, pathological and follow-up data of 188 gastric cancer patients who underwent laparoscopy-assisted total gastrectomy at Department IV of Gastrointestinal Cancer Center, Peking University Cancer Hospital, from April 2009 to December 2016 were collected for a retrospective cohort study.@*INCLUSION CRITERIA@#ECOG performance score 0-1; preoperative gastroscopy discovered gastric masses, and pathological biopsy confirmed adenocarcinoma; distant metastases were excluded by image examination; preoperative cardiopulmonary function was normal; preoperative blood routine test, liver and renal function, and coagulation function were normal; laparoscopy-assisted total gastrectomy was performed.@*EXCLUSION CRITERIA@#intraoperative laparoscopic exploration indicated abdominal and/or pelvic peritoneal metastasis; free cancer cells in peritoneal cavity; conversion to laparotomy during laparoscopic surgery. Patients were divided by age into 2 groups, ≥ 65 years old group(59 cases) and 0.05). Multivariate logistic regression analysis showed that preoperative comorbidities(OR=0.223, 95%CI0.053 to 0.944, P=0.041) was an independent risk factor for postoperative complications in patients aged ≥ 65 years old undergoing laparoscopy-assisted total gastrectomy. The median survival time was 21.3 months and the overall 5-year survival rate was 50.0%. The 5-year survival rate was 45.5% and 57.5% in patients aged ≥ 65 and < 65 years, respectively, and there was no significant difference(P=0.205).@*CONCLUSIONS@#Laparoscopy-assisted total gastrectomy is safe and effective in the treatment of gastric cancer patients ≥ 65 years old. Age is not a contraindication of laparoscopy-assisted total gastrectomy.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Complicações Pós-Operatórias
/
Neoplasias Gástricas
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Cirurgia Geral
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Estudos Retrospectivos
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Estudos de Coortes
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Resultado do Tratamento
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Laparoscopia
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Gastrectomia
Tipo de estudo:
Estudo de etiologia
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Estudo de incidência
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Estudo observacional
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Fatores de risco
Limite:
Idoso
/
Humanos
Idioma:
Chinês
Revista:
Chinese Journal of Gastrointestinal Surgery
Ano de publicação:
2018
Tipo de documento:
Artigo