Perioperative Restrictive Red Blood Cell Transfusion:Recent Advances in Research and Clinical Guidelines / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 541-547, 2019.
Article
em Zh
| WPRIM
| ID: wpr-775997
Biblioteca responsável:
WPRO
ABSTRACT
Perioperative restrictive red blood cell(RBC)transfusion strategy,in which a trigger of hemoglobin(Hb)<7 g/dl is used,is of great benefits to save blood storage and reduce transfusion-related adverse events including infections,immunologic risks,and circulatory overload.Human body can display a series of compensatory mechanisms to acute anemia,including increased cardiac output,favored oxyhemoglobin dissociation,and lung vascular dilation.Therefore,moderate Hb decrease does not necessarily lead to hypoxemia.Patients undergoing hip surgery or suffering from septic shock and/or upper gastrointestinal bleeding can benefit from restrictive RBC transfusion;however,restrictive transfusion may be associated with adverse outcomes in patients with coronary heart disease or undergoing cardiac surgery.Restrictive RBC transfusion strategies have been included in described in many different guidelines.Most of them recommended Hb<7 g/dl to be a trigger for allogeneic RBC transfusion.For patients with an Hb of 7-10 g/dl,the application of restrictive RBC transfusion should be based on the expected blood loss,compensatory ability,and metabolic rate.
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Procedimentos Cirúrgicos Operatórios
/
Hemoglobinas
/
Guias de Prática Clínica como Assunto
/
Transfusão de Eritrócitos
/
Assistência Perioperatória
Tipo de estudo:
Guideline
Limite:
Humans
Idioma:
Zh
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2019
Tipo de documento:
Article