Congenital disorders of glycosylation and liver diseases / 临床肝胆病杂志
Journal of Clinical Hepatology
; (12): 1684-1689, 2019.
Article
em Zh
| WPRIM
| ID: wpr-779041
Biblioteca responsável:
WPRO
ABSTRACT
Congenital disorders of glycosylation (CDGs) is a group of inherited metabolic diseases caused by abnormal glycosylation of protein or lipids, and the number of CDGs are increasing rapidly in recent years. With the advent and popularization of next-generation sequencing, more and more disorders associated with glycosylation-related gene mutations have been discovered. Synthesis of glycoproteins and glycolipids is one of the major roles of the liver, and many CDGs affect hepatobiliary structure or function and may lead to fatty liver disease, liver fibrosis, and ductal plate malformation. This article reports the latest advances in the pathogenesis, diagnosis, and treatment of CDGs and related liver diseases.
Texto completo:
1
Base de dados:
WPRIM
Idioma:
Zh
Revista:
Journal of Clinical Hepatology
Ano de publicação:
2019
Tipo de documento:
Article