Irinotecan (CPT-11)-induced hemorrhagic colitis / 대한내과학회지
Korean Journal of Medicine
; : 688-691, 2002.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-77930
Biblioteca responsável:
WPRO
ABSTRACT
Irinotecan (CPT-11) is a chemotherapeutic agent that inhibits topoisomerase I and has shown efficacy against advanced colorectal cancer. Diarrhea is the most common toxicity that has been reported to be as high as 87% in patients treated with irinotecan. However, the serious complications including acute hemorrhagic colitis, intestinal ulceration, and intestinal perforation may be uncommon events with irinotecan therapy. We report the first Korean case of acute hemorrhagic colitis induced by irinotecan administration in the patient with advanced colon cancer.
Texto completo:
Disponível
Contexto em Saúde:
Doenças Negligenciadas
Problema de saúde:
Diarreia
/
Doenças Negligenciadas
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Úlcera
/
Neoplasias Colorretais
/
Colite
/
Neoplasias do Colo
/
DNA Topoisomerases Tipo I
/
Diarreia
/
Perfuração Intestinal
Limite:
Humanos
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Ano de publicação:
2002
Tipo de documento:
Artigo