Healing of Injury of Meniscus Using Fibrin Glue and Meniscal Cell in Rabbit Model / 대한정형외과연구학회지
Journal of Korean Orthopaedic Research Society
; : 265-273, 2003.
Article
em Ko
| WPRIM
| ID: wpr-7812
Biblioteca responsável:
WPRO
ABSTRACT
PURPOSE: We attempt to heal the defect of meniscus using fibrin glue and allogenic meniscal cells in rabbit. MATERIALS AND METHODS: Meniscal cells were isolated from medial meniscus of knee joint of rabbit and cultured and expanded in vitro. The mixture of fibrin glue and meniscal cells implanted to the defect of rabbit meniscus. Examination of gross morphology, histological and immunohistochemical staining of retrieved specimens were performed at 3 and 6 weeks. RESULTS: Cultured cells uniformly displayed an elongated, fibroblastic and fibrocartilagenous morphology. The histological and immunohistochemical analysis revealed regeneration of meniscal tissue at the defect site. CONCLUSION: Meniscal cell transplantation with fibrin glue resulted in the regeneration of meniscus tissue successfully in rabbit model. This approach could be applied for treatment of meniscus injury.
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Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Regeneração
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Meniscos Tibiais
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Fibrina
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Adesivo Tecidual de Fibrina
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Células Cultivadas
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Transplante de Células
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Transplantes
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Fibroblastos
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Articulação do Joelho
Idioma:
Ko
Revista:
Journal of Korean Orthopaedic Research Society
Ano de publicação:
2003
Tipo de documento:
Article