Involvement of “anger” in Effectiveness of Yokukansan/Yokukansankachimpihange / 日本東洋医学雑誌

ABSTRACT

There is a well-­known “kuketsu traditional oral instruction for using Kampo formula”, for yokukansan and yokukansankachimpihange (yokukansan group) which mentioned about the importance of existence of “an­ger”. It says that responders to yokukansan group are likely to be irascible. However, no statistically analyzed report about the accuracy of this “kuketsu” is published to date. Therefore, we retrospectively analyzed the charts of patients at one institution who had been treated with yokukansan group by multivariate analysis. We selected amelioration of their chief complaints as dependent variable ; ten items from inquiry as independent variables. The number of patients was 32 (male 12, female 20), mean age was 47.3. “Gender” and “irascible” were statistically significant in logistic regression analysis. The adjusted odds ratio of male versus female was 21.7, while being “irascible” versus not being “irascible” was 8.2. Yokukansan group seemed to be more ef­fective if patients were male or irascible in this study.