Meta-analysis on risk stratification of malignant ventricular tachyarrhythmic events in arrhythmogenic right ventricular cardiomyopathy / 영남의대학술지
Yeungnam University Journal of Medicine
; : 208-215, 2017.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-787072
Biblioteca responsável:
WPRO
ABSTRACT
BACKGROUND:
Arrhythmogenic right ventricular cardiomyopathy (ARVC) is a cardiomyopathy characterized by predominant right ventricular fibro-fatty replacement, right ventricular dysfunction and ventricular arrhythmias. It is a rare but important cause of sudden cardiac death in children and young adults. A meta-analysis on risk stratification of major ventricular tachyarrhythmic events indicating the need for implantable cardioverter defibrillator therapy in ARVC was performed.METHODS:
The pubmed database was searched from its inception to May 2015. Of the 433 citations identified, 12 were included in this meta-analysis. Data regarding major ventricular tachyarrhythmic events were retrieved in 817 subjects from the studies. For the variables, a combined odds ratio (OR) was calculated using a fixed-effects meta-analysis.RESULTS:
Extensive right ventricular dysfunction (OR, 2.44), ventricular late potential (OR, 1.66), inducible ventricular tachyarrhythmia during electrophysiology study (OR, 3.67), non-sustained ventricular tachycardia (OR, 3.78), and history of fatal event/sustained VT (OR, 5.66) identified as significant risk factors (p < 0.0001).CONCLUSION:
This meta-analysis shows that extensive right ventricular dysfunction, ventricular late potential, inducible ventricular tachyarrhythmia during electrophysiological study, non-sustained ventricular tachycardia, and history of sustained ventricular tachycardia/fibrillation are consistently reported risk factors of major ventricular tachyarrhythmic events indicating implantable cardioverter defibrillator therapy in patients with ARVC.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Arritmias Cardíacas
/
Taquicardia
/
Razão de Chances
/
Fatores de Risco
/
Morte Súbita Cardíaca
/
Taquicardia Ventricular
/
Disfunção Ventricular Direita
/
Displasia Arritmogênica Ventricular Direita
/
Morte Súbita
/
Desfibriladores
Tipo de estudo:
Estudo de etiologia
/
Estudo prognóstico
/
Fatores de risco
/
Revisão sistemática
Limite:
Criança
/
Humanos
Idioma:
Inglês
Revista:
Yeungnam University Journal of Medicine
Ano de publicação:
2017
Tipo de documento:
Artigo