Olaparib:a new drug for hereditary ovarian cancer treatment / 药学实践杂志
Journal of Pharmaceutical Practice
; (6): 373-375, 2015.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-790490
Biblioteca responsável:
WPRO
ABSTRACT
Olaparib is an inhibitor of poly (ADP-ribose) polymerase (PARP) enzymes ,and was developed by AstraZen-eca Pharmaceuticals LP .Olaparib has therapeutic potential for treating cancers associated with impaired DNA repair capabili-ties ,particularly those with deficiencies in the homologous recombination repair (HRR) pathway .Olaparib is an available ther-apy option for ovarian cancer patients with deficiencies in the BRCA 1 and BRCA2 genes .Olaparib can selectively kill cancer cells without compromising normal cells .Compared to traditional chemotherapy means ,adverse reactions are much smaller .
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Journal of Pharmaceutical Practice
Ano de publicação:
2015
Tipo de documento:
Artigo