A study on direct economic burden of chronic hepatitis B-relevant diseases / 预防医学

ABSTRACT

Objective To explore the economic burden of chronic hepatitis B -relevant diseases and to understand the factors associated with the economic burden. Methods Economic - related information was collected by questionnaire investigation in Ningbo City. Hospital records and hospitalization expenses were obtained when 630 patients discharged from hospital. Influencing factors of the economic burden were analyzed by stepwise multiple linear regressions. Results The average of the total cost for the diseases was 65 139. 51 Yuan. Direct medicinal and non-medical costs were 61 606. 78 Yuan and 3 532. 73 Yuan respectively. The total annual costs for primary carcinoma of the liver,chronic severe hepatitis B,Hepatitis cirrhosis and chronic hepatitis B were 123 571. 78 Yuan,93 278. 65 Yuan,82 467. 99 Yuan and 21 824. 31 Yuan respectively. The average ratio of direct medical to direct non-medical cost was 17. 44,in which primary carcinoma of the liver,hepatitis cirrhosis,chronic severe hepatitis B,chronic hepatitis B were 19. 17,15. 52,21. 62 and 17. 02 respectively. The total cost was 1. 75 times higher than annual income of individual,as well as 1. 02 times higher than household income. Occupation,complication,income,diagnosis results were the influencing factors for economic burden. Conclusion The economic burden of chronic hepatitis B-relevant diseases was enormous in Ningbo City. The cost of direct medical was larger than direct non -medical. Expenses increased dramatically as the disease progressed to more advanced stage.