Promotion of wound healing via regulating the polarization of macrophage by mesenchymal stem cells / 中华整形外科杂志
Chinese Journal of Plastic Surgery
; (6): 1275-1278, 2019.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-800224
Biblioteca responsável:
WPRO
ABSTRACT
How to promote rapid wound healing and reduce scar hyperplasia is an urgent problem to be solved in plastic surgery. Mesenchymal stem cells (MSCs) is a research hotspot in current cell therapy. The author reviewed the literature and summarized the mechanism of the MSCs effect on the macrophage. MSCs release multiple soluble cytokines, leading the polarization of anti-inflammatory type M2 cell which can reduce the inflammatory cytokines and promote tissue repair and regeneration.The writer concluded that the polarization effect of mesenchymal stem cells on macrophages provides a new therapeutic strategy and theoretical basis for solving the problem of wound healing.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Journal of Plastic Surgery
Ano de publicação:
2019
Tipo de documento:
Artigo