Spatial organization of neurons, astrocytes and vessels in rat brain / 中南大学学报(医学版)

ABSTRACT

OBJECTIVE@#To demonstrate the spatial organization of neurons, astrocytes and vessels in rat brain.@*METHODS@#Cerebral vascular was shown by vivi-perfusion with ink. Glial fibrillary acidic protein (GFAP) immunohistochemistry and nissl's staining were performed on the serial sections of frozen brain tissues.@*RESULTS@#Astracytes distributed along the branches of blood vessels, and neurons in the region of the relatively rich blood vessels. Neurons and astrocytes presented regional distribution.@*CONCLUSION@#This method can well indicate the spatial organization of neurovascular unit, the regional differences in the distribution may be related to physical activities and the corresponding adjustment function.