Effect of birid triple viable on peptic ulcer patients with Helicobacter pylori infection / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 1000-1004, 2010.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-814365
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE@#To observe the effect of birid triple viable on peptic ulcer patients with Helicobacter pylori(H.pylori) infection.@*METHODS@#A total of 120 peptic ulcer patients with H.pylori infection was randomly divided into 2 groups. The control group was treated with the triple therapy including Esomeprazole, Amoxicillin, and Furazolidone. The treatment group was treated with the same triple therapy plus birid triple viable. The pH values of the gastric juice, bacterial culture of the gastric juice, the therapy-related side effects and the healing rate of ulcer and erosive were observed before the treatment and after a 14-day-treatment respectively. The (14)C-urea breath test((14)C-UBT) was used to evaluate the H.pylori eradication rates 4 weeks after the treatment.@*RESULTS@#After the treatment, pH values of the gastric juice in both groups were significantly higher than those before the treatment (P0.05),while the healing rate of erosion in the treatment group was higher than that of the control group (P<0.05).The H.pylori eradication rates evaluated by per-protocol (PP) analysis in the treatment group was significantly higher than that of the control group (80.4% and 62.4% respectively, P<0.05).@*CONCLUSION@#The combined use of birid triple viable and the triple therapy of H.pylori in peptic ulcer patients with H.pylori infection can reduce the bacteria of the gastric juice and therapy-related side effects. It can increase the H.pylori eradication rate and promote the healing of erosion.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Úlcera Péptica
/
Fisiologia
/
Esquema de Medicação
/
Helicobacter pylori
/
Infecções por Helicobacter
/
Tratamento Farmacológico
/
Quimioterapia Combinada
/
Esomeprazol
/
Furazolidona
/
Amoxicilina
Tipo de estudo:
Guia de prática clínica
Limite:
Adulto
/
Feminino
/
Humanos
/
Masculino
Idioma:
Chinês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2010
Tipo de documento:
Artigo