Genetics of autism spectrum disorders / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 703-711, 2011.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-814530
Biblioteca responsável:
WPRO
ABSTRACT
Autism is a group of etiology and clinical heterogeneous neurodevelopmental disorders with an onset before 3 years old. It has 3 core characteristics deficits in verbal communication; impairment of social interaction; restricted interests and repetitive behaviors. The incidence is increasing over time worldwide. Twin and family studies have demonstrated that autism has a high heritability (>90%). Although certain progress of autism genetic study has been made in the last decades and several autism susceptibility genes and loci have been identified, there are still about 70%-80% of patients for whom an autism-related genetic change cannot be identified.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Transtorno Autístico
/
Heterogeneidade Genética
/
Epigenômica
/
Genética
Tipo de estudo:
Estudo prognóstico
Limite:
Criança, pré-escolar
/
Humanos
/
Lactente
Idioma:
Inglês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2011
Tipo de documento:
Artigo