Correlation between ABCC11 gene single nucleotide polymorphism and the incidence of axillary osmidrosis in Chinese Han population / 中南大学学报(医学版)
Journal of Central South University(Medical Sciences)
; (12): 1141-1145, 2013.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-814810
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE@#To explore the relationship between ABCC11 gene single nucleotide polymorphism (SNP) and the incidence of axillary osmidrosis in Chinese Han population.@*METHODS@#The genotype of ABCC11 gene SNP at rs17822931 in 40 patients with axillary osmidrosis and 5 normal Han people was detected and analyzed by high resolution melt and gene sequencing.@*RESULTS@#The detection of the genotype of ABCC11 gene SNP at rs17822931 showed that 37 of the 40 patients were GA genotype and the other 3 were GG genotype, while the 5 normal subjects were AA genotype.@*CONCLUSION@#SNP in ABCC11 is the genetic cause of axillary osmidrosis. GG or GA leads to axillary osmidrosis, while AA allele presents the absence of axillary osmidrosis.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Axila
/
Doenças das Glândulas Sudoríparas
/
Incidência
/
Transportadores de Cassetes de Ligação de ATP
/
Polimorfismo de Nucleotídeo Único
/
Povo Asiático
/
Alelos
/
Frequência do Gene
/
Genética
/
Genótipo
Tipo de estudo:
Estudo de incidência
/
Estudo prognóstico
Limite:
Humanos
Idioma:
Chinês
Revista:
Journal of Central South University(Medical Sciences)
Ano de publicação:
2013
Tipo de documento:
Artigo