Multicenter cross-sectional study of surgical site infection after emergency surgery in China / 中国实用外科杂志

ABSTRACT

OBJECTIVE: To understand the current status of surgical site infection(SSI)after emergency abdominal surgery(EAS) in China,and to discuss the risk factors.METHODS: The study included 293 adult patients who underwent EAS in 26 hospitals in China in May 2018. The basic information, perioperative data, and microbial culture results of infected incisions were collected prospectively. The primary outcome measure was the incidence of surgical site infection within 30 days after surgery. Secondary outcome variables were postoperative hospital stay,ICU occupancy,ICU stay,treatment costs,and postoperative30-day mortality.RESULTS: Twenty-two(7.5%) patients developed SSI after surgery.The main pathogen of SSI is Escherichia coli [culture positive rate was 36.4%(8/22)]. Patients with SSI had a significantly longer overall hospital stay and ICUstay,and ICU occupancy and treatment were significantly higher. Multivariate logistic regression analysis showed thatmales(P=0.030) and operative time(P=0.007) were risk factors for SSI. Laparoscopic surgery(P=0.022)was aprotective factor for SSI.CONCLUSION: The incidence of SSI after EAS in China is 7.5%,and SSI leads to a significantincrease in the medical burden of patients. Choosing laparoscopic surgery can reduce the incidence of SSI after EAS.Controlling preoperative blood glucose may have positive significance in preventing SSI after EAS.