Relationship of adrenal insufficiency with metabolic crisis and sudden death / 中国实用儿科杂志

ABSTRACT

Adrenal insufficiency(AI)is a type of adrenocortical hormone-deficient lesion caused by primary or secondary factors. Because of its lack of specificity in clinical manifestations,it is difficult to identify early,which may lead to delayed diagnosis. If the treatment is not timely,it may cause adrenal crisis(AC)or even sudden death. Sudden death in children due to adrenal insufficiency may be directly related to hyperkalemia caused by adrenal crisis. Gastrointestinal illness and infections are common precipitant for an adrenal crisis. Despite it being a treatable condition for now,failure of adequate preventive measures or delayed treatment has often led to unnecessary deaths. Therefore,more measures are needed to prevent the adrenal crisis and to ensure that appropriate emergency medical services are established after the crisis to reduce the rate of sudden death.