Effect of beta-tricalcium phosphate/poly-l-lactide composites on radial bone defects of rabbit
Asian Pacific Journal of Tropical Medicine
; (12): 753-756, 2013.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-819971
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE@#To explore the effect ofβ-TCP/PLLA scaffold in repairing rabbit radial bone defects.@*METHODS@#Thirty New Zealand rabbits were divided into β-TCP /PLLA group (group A), pure PLLA group (group B) and contrast group (group C) randomly. The rabbits were sacrificed respectively after 4, 8, 12, 24 weeks and the X-ray film was performed at the same time to evaluate the repair effect in different groups.@*RESULTS@#X-ray film showed there was uneven low density bone callus development in defect region after 4 weeks in group A. The defect region was filled with neonate osseous tissue completely during 12-24 weeks. X-ray score revealed that repair of bone defect results significantly better than group B and group C.@*CONCLUSIONS@#The β-TCP /PLLA composite is capable of repairing radial bone bone defects. β-TCP/PLLA scaffold is significant because of rapid degradation ability, good histocompatibility and osteogenic action.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Poliésteres
/
Polímeros
/
Rádio (Anatomia)
/
Cirurgia Geral
/
Anormalidades Congênitas
/
Terapêutica
/
Fenômenos Biomecânicos
/
Doenças Ósseas
/
Fosfatos de Cálcio
/
Densidade Óssea
Limite:
Animais
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Asian Pacific Journal of Tropical Medicine
Ano de publicação:
2013
Tipo de documento:
Artigo