Cushing Disease Diagnosed with Bilateral Simultaneous Inferior Petrosal Sinus Sampling
Journal of the Korean Academy of Family Medicine
; : 746-751, 2003.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-82547
Biblioteca responsável:
WPRO
ABSTRACT
The most common endogenous cause of Cushing's syndrome is Cushing's disease. The evaluation of patients with suspected Cushing's disease and syndrome requires an understanding of the proper use and limitations of the tests commonly included in the diagnostic work-up. The best screening test for Cushing's syndrome is a 24-hour urine collection with analysis for urinary free cortisol excretion. Low-dose and high-dose dexamethasone suppression tests, corticotropin assays, a corticotropin-release hormone stimulation test and inferior petrosal sinus cathaterization may be required for a definitive diagnosis. MRI is useful in localizing the lesion but some limitations. Surgical removal of the lesion by a trans-sphenoidal appraoch is usually successful, but long-term follow-up is required. We report a case of Cushing disease which shows such typical clinical characteristics of Cushing syndrome as weight gain, skin lesions, truncal obesity, striae, hypertension.
Texto completo:
Disponível
Contexto em Saúde:
ODS3 - Saúde e Bem-Estar
/
ODS3 - Meta 3.4 Reduzir as mortes prematuras devido doenças não transmissíveis
Problema de saúde:
Meta 3.4: Reduzir as mortes prematuras devido doenças não transmissíveis
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Hipertensão Arterial
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Doença Cardiovascular
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Doenças do Sistema Endócrino
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Pele
/
Dexametasona
/
Hidrocortisona
/
Imageamento por Ressonância Magnética
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Aumento de Peso
/
Programas de Rastreamento
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Seguimentos
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Amostragem do Seio Petroso
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Hormônio Adrenocorticotrópico
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Síndrome de Cushing
Tipo de estudo:
Estudo diagnóstico
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Estudo observacional
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Estudo prognóstico
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Estudo de rastreamento
Limite:
Humanos
Idioma:
Coreano
Revista:
Journal of the Korean Academy of Family Medicine
Ano de publicação:
2003
Tipo de documento:
Artigo