Evaluation of Erythrocyte Iron Incorporation in Beijing Prepubertal Children Using a Single Stable Isotope Tracer Method / 生物医学与环境科学(英文)
Biomedical and Environmental Sciences
; (12): 414-420, 2020.
Article
em En
| WPRIM
| ID: wpr-828998
Biblioteca responsável:
WPRO
ABSTRACT
Objective@#To analyze the rate of erythrocyte iron incorporation and provided guidance for the iron nutrition for prepubertal children.@*Methods@#Fifty-seven prepubertal children of Beijing were involved in this study and each subject was orally administered 3 mg of Fe twice daily to obtain a total of 30 mg Fe after a 5-d period. The stable isotope ratios in RBCs were determined in 14th day, 28th day, 60th day, and 90th day. The erythrocyte incorporation rate in children was calculated using the stable isotope ratios, blood volume and body iron mass.@*Results@#The percentage of erythrocyte Fe incorporation increased starting 14 th day, reached a peak at 60 d (boys: 19.67% ± 0.56%, girls: 21.33% ± 0.59%) and then decreased. The erythrocyte incorporation rates of Fe obtained for girls in 60th day was significantly higher than those obtained for boys ( < 0.0001).@*Conclusions@#The oral administration of Fe to children can be used to obtain erythrocyte iron incorporation within 90 d. Prepubertal girls should begin to increase the intake of iron and further studies should pay more attention to the iron status in prepubertal children.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Espectrometria de Massas
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Eritrócitos
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Pequim
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Ferro
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Isótopos de Ferro
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Metabolismo
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Métodos
Limite:
Child
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Female
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Humans
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Male
País/Região como assunto:
Asia
Idioma:
En
Revista:
Biomedical and Environmental Sciences
Ano de publicação:
2020
Tipo de documento:
Article