Study on chemical constituents of Petasites japonicus / 第二军医大学学报

ABSTRACT

Objective: To isolate and identify the chemical constituents in the rhizome of the Petasites ja ponicus. Methods: Dried rhizome of Petasites ja ponicus were subjected to extraction with EtOH, and the chemical constituents in the extract were isolated and their structures were identified by physicochemical properties and spectral analysis. Results: Five compounds were obtained and identified from the rhizome of Petasites ja ponicus, inlcuding as β-sitoterol (I), ergosterol (II), bakkenolide-B (III), bakkenolide-D (IV) and furanofukinol (V). Conclusion: Compound (II) has been obtained from Petasites japonicus for the first time.