Effect evaluation on application of gallnut extract in root canal therapy of patients with chronic periapical periodontitis / 吉林大学学报(医学版)

ABSTRACT

Objective: To explore the influence of gallnut extract as a root canal irrigants in the curative effect of chronic periapical periodontitis, and to clarify its mechanism. Methods: A total of 192 patients diagnosed with chronic periapical periodontitis were selected and randomly divided into control group (distilled water), hydrogen peroxide group, sodium hypochlorite group and gallnut extract group (n=48). In the process of root canal treatment, four irrigants were used respectively, then the curative effects 1 week, 6 months, 12 months after treatment were observed and compared. Results: After root filling treatment, the cold and heat stimulation of the tooth was insensitive in clinical examination, percussion (-), loose degree≤ I°, no swollen gums, bleeding on probing (-), no fistula, normal function of the exercise of chewing, decreased or disappeared transmission area in periapical bone in X-ray photo, and those metioned above were considered effective treatment. After 6 months of treatment, the effective rate in gallnut group was 89.4%, and there were no statistically significant differences compared with hydrogen peroxide group (91. 1%) and sodium hypochlorite group (91. 5%) (P>0. 05), but there was significant difference compared with control group (67.4%) (P0. 05), but the ratio of tooth from improvement to recovery in gallnut group was higher than those in hydrogen peroxide group and sodium hypochlorite group. Conclusion: Gallnut extract as a root canal irrigants has good antibacterial and cleaning effect, and can achieve the aim of curing the chronic root periapical inflammation and preventing the infection.