Correlation of serum β2-microglobulin expression with the clinical characteristics and prognosis of mantle-cell lymphoma / 肿瘤
Tumor
; (12): 642-649, 2017.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-848533
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To investigate the correlation of serum β2-microglobulin (β2-MG) with overall survival and mantle-cell lymphoma international prognostic index (MIPI) of patients with mantle-cell lymphoma (MCL).Methods:
The clinical data of 61 MCL patients admitted in Tianjin Medical University Cancer Institute and Hospital were retrospectively analyzed. Fisher's exact test was used to analyze the relationship between serum β2-MG level and the clinical features of MCL patients. COX proportional hazards model was used to analyze the influencing factors of prognosis in MCL patients.Results:
In total of 61 MCL patients, 35 (57.4%) had abnormal elevation of serum β2-MG. The level of serum β2-MG was significantly associated with clinical stage (P = 0.011), B symptom (P = 0.032), bone marrow (P 2.5 mg/L have a poor overall survival as compared with the pateints with serum β2-MG ≤2.5 mg/L.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
Idioma:
Chinês
Revista:
Tumor
Ano de publicação:
2017
Tipo de documento:
Artigo