A Case of Subcutaneous Panniculitis-like T Cell Lymphoma in Childhood
Journal of the Korean Pediatric Society
; : 1028-1032, 2002.
Article
em Ko
| WPRIM
| ID: wpr-85067
Biblioteca responsável:
WPRO
ABSTRACT
Subcutaneous pannicultis-like T cell lymphoma is a rare cutaneous T cell lymphoma. It presents with multiple subcutaneous nodules or plaques involving the extremities or trunk, and with constitutional symptoms that include fever, malaise, fatigue, myalgia, chills and weight loss. Histologically, the lesions of this disease are reminiscent of panniculitis and are composed of a mixture of small and large atypical lymphoid cells infiltrating between adipocytes. The optimal treatment for this disease is undefined and prognosis of this disease is poor, even when treated with multiagent chemotherapy regimens considered optimal for agressive lymphoma of other types. Poor prognosis factors include clinical features such as anemia, leukocytopenia, hepatosplenomegaly, lymphadenopathy and coagulopathy, which are suggestive of hemophagocytosis. Much of the mortality of this disease is due not to disseminated lymphoma with organ failure, but rather to complications of the cytopenias associated with the hemophagocytic syndrome. We report a case of subcutaneous panniculitis-like T cell lymphoma in a 12 year-old boy who presented with initial complaints of fever and multiple subcutaneous nodules, and briefly review the related literature.
Palavras-chave
Texto completo:
1
Base de dados:
WPRIM
Assunto principal:
Prognóstico
/
Linfócitos
/
Paniculite
/
Redução de Peso
/
Mortalidade
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Linfoma de Células T
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Linfoma Cutâneo de Células T
/
Adipócitos
/
Calafrios
/
Tratamento Farmacológico
Tipo de estudo:
Prognostic_studies
Limite:
Child
/
Humans
/
Male
Idioma:
Ko
Revista:
Journal of the Korean Pediatric Society
Ano de publicação:
2002
Tipo de documento:
Article