Effect of traditional Chinese medicine Jiegusan on bone metabolism in patients with humeral fracture / 中草药

ABSTRACT

Objective: To study the effect of Jiegusan on bone metabolism in patients with humeral fracture. Methods: Totally 128 patients with humeral fracture were divided into the treatment group and control group, and then to observe the influence of Jiegusan on bone metabolism in the patients. Results: Symptoms such as swelling and pain in treatment group were significantly improved after treatment with Jigusan than control group. After treatment, serum osteocalcin and alkaline phosphatase in the treatment were significantly higher (P < 0.05) and serum D-dimer production was significantly lower than that in the control group, while serum calcium level in serum showed no difference between the experimental and control group. Conclusion: Jiegusan can accelerate fracture healing via regulating the bone metabolism and play a role in anticoagulant activity via lowering the level of serum D-dimer.