Study on preparation technology of Compound Jianshen Granules / 中草药
Chinese Traditional and Herbal Drugs
; (24): 3810-3816, 2016.
Article
em Zh
| WPRIM
| ID: wpr-853183
Biblioteca responsável:
WPRO
ABSTRACT
Objective: To optimize the extracting and processing conditions of Compound Jianshen Granules (CJG). Methods: UV analytical methods of total saponin and total polysaccharides were established, the optimal ethanol extraction process and water extraction process were confirmed according to single factor and orthogonal design test. The influence of different excipients and wetting agents were investigated, taking forming rate, solubility, and absorption rate as indexes, the materials added prescription varieties, ratio, and optimum molding process were screened. Results: The optimal ethanol extraction technology of CJG was: 85% ethanol, 10-fold, extracting for three times, 2 h once. The optimal water extraction technology was 14-fold, decocting 3 times, 30 min once. The optimized conditions of CJG were obtained with: accessories for the dextrin: lactose (4:1), main drug-accessories (1:1), with 85% ethanol as wetting agent which accounted for 15% of the main drug. Conclusion: The extraction process and forming process are feasible and stable, and the quality is controllable.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Traditional and Herbal Drugs
Ano de publicação:
2016
Tipo de documento:
Article