Chemical constituents in stems of Ilex cornuta / 中草药
Chinese Traditional and Herbal Drugs
; (24): 891-896, 2016.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-853635
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To investigate the chemical constituents in the stems of Ilex cornuta and the ability of scavenging free radicals of compounds 1-9.Methods:
The compounds were isolated and purified by silica gel, medium pressure column chromatography, and semi-preparative liquid chromatography, and their structures were elucidated by chemical properties and spectroscopic analyses. The antifreeradical efficiency of compounds 1-9 was evaluated by DPPH radical scavenging assay.Results:
Fifteen compounds were isolated and their structures were identified as isochlorogenic acid B (1), 3,4,5-tricaffeoylquinic acid (2), 4,5-di-O-caffeoyl quinic acid methyl ester (3), 3,4-di-O-caffeoyl quinicacid methyl ester (4), 3,5-di-O-caffeoyl quinicacid methyl ester (5), 3,4,5-tri-O-caffeoyl quinic acid methyl ester (6), 3,5-dimethoxy-4-hydroxybenzaldehyde (7), ethyl gallate (8), dihydrosyringenin (9), 2,6-dimethoxy-1,4-benzoquinone (10), arctigenin (11), 1-O-(vanillic acid)-6-O-(3″, 5″-dimethoxy-galloyl)-β-D-glycoside (12), (+)-1-hydroxypinoresinol-1-O-β-D-glucopyranoside (13), (+)-(7S,8S)-syringylglycerol 8-O-β-D-glucopyranoside (14), and schaftoside (15). Compounds 1-7 had good antifreeradical efficiency.Conclusion:
Compounds 6,8-10,14, and 15 are obtained from the plants of Ilex L. the first time, and compounds 2,7,11, and 12 are obtained from this plant for the first time. Compounds 1-6 have good antifreeradical efficiency.
3,4,5-tri-O-caffeoyl quinic acid methyl ester; 3,4,5-tricaffeoylquinic acid; 3,4-di-O-caffeoyl quinicacid methyl ester; 3,5-di-O-caffeoyl quinicacid methyl ester; 3,5-dimethoxy-4-hydroxybenzaldehyde; 4,5-di-O-caffeoyl quinic acid methyl ester; Anti-oxidant activity; Ilex cornuta Lindl. et Paxt; Isochlorogenic acid B
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Traditional and Herbal Drugs
Ano de publicação:
2016
Tipo de documento:
Artigo