Chemical constituents in whole herb of Euphorbia lunulata / 中草药

ABSTRACT

Objective: To study the chemical constituents in the whole herb of Euphorbia lunulata. Methods: The compounds were separated and purified by silica gel and Sephadex LH-20 column chromatography. The structures of the compound were identified on the basis of chemical and spectral methods. Results: Seventeen compounds were isolated from 90% ethanol extract from the whole herbs of E. lunulata and identified as 1-octacosanol (1), β-sitosterol (2), octadecyl caffeate (3), cycloart-23Z-en-3β, 25-diol (4), scopoletion (5), 24-methylenecycloartanol (6), stigmasterol (7), vifolin (8), o-phthalic acid bis-(2-ethyl decyl)-ester (9), ferulic acid hexacosyl ester (10), scopoletin-7-glucoside (11), β-amyrin (12), gallic acid (13), sucrose (14), 17-hxdroxyjolkinolide A (15), jolkinolide A (16), and jolkinolide B (17). Conclusion: Compounds 1,3,8-12 and 14-17 are isolated from this plant for the first time, and compound 9 is isolated from the plants of Euphorbia L. for the first time.