Poikiloderma Vasculare Atrophicans Showing Features of Ashy Dermatosis in the Beginning
Annals of Dermatology
; : 197-200, 2015.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-8537
Biblioteca responsável:
WPRO
ABSTRACT
Poikiloderma vasculare atrophicans (PVA) is a rare poikilodermatous variant of early-stage mycosis fungoides characterized by generalized poikiloderma, atrophy, mottled dyspigmentation, and telangiectasia. In 2001, a 14-year-old male presented with asymptomatic brownish-gray polymorphic macules throughout the body with flexural accentuation. A skin biopsy showed increased melanophages with focal hydropic changes. Ashy dermatosis was considered a possible diagnosis. In 2005, the lesions began to show darkening and lichenification in the lower part of the trunk. In 2011, his skin showed definite poikilodermatous changes, and a biopsy showed band-like inflammatory infiltrations of atypical lymphocytes, epidermal atrophy, and epidermotropism of predominantly CD4-CD8+ atypical T cells. In addition, results of T-cell receptor gene rearrangement analysis were positive. Based on the aforementioned findings, he was diagnosed with PVA. If a patient shows long-standing and progressive hyperpigmentary skin changes, periodic follow-up and repeated skin biopsies are recommended to determine the underlying condition.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Atrofia
/
Pele
/
Dermatopatias
/
Telangiectasia
/
Biópsia
/
Linfócitos
/
Linfócitos T
/
Seguimentos
/
Micose Fungoide
/
Relação CD4-CD8
Tipo de estudo:
Estudo diagnóstico
/
Estudo observacional
/
Estudo prognóstico
Limite:
Adolescente
/
Humanos
/
Masculino
Idioma:
Inglês
Revista:
Annals of Dermatology
Ano de publicação:
2015
Tipo de documento:
Artigo