The Drug Safety and Rational Use of Zolpidem Tartrate / 中国药学杂志

ABSTRACT

OBJECTIVE: To givesafety recommendations for the dose, time of administration, and precautions for zolpidem tartrate. METHODS: Search relevant websites and databases, the pharmaceutical characteristics, clinical application, adverse reactions, drug interactions and rational use of zolpidem tartrate were reviewed. RESULT:S In order to ensure the safety of medication for patients, it is recommended that women and the elderly aged 65 years and above should use the minimum effective dose of 5 mg•d-1. Short-term use, the course of medication should not exceed 4 weeks. Insomnia patients can choose to treat as needed (intermittent, not every night). Follow the prescribed course of treatment and dosage in strict accordance with the doctor's advice. CONCLUSIONS: Zolpidem tartrate can treat various types of insomnia with definite curative effect and mild adverse reactions.Clinicians and pharmacists should pay attention to the safety risks of zolpidem and inform patients of the contraindications and precautions.