Quality Control Method of Xinmaishu Capsules / 中国药学杂志
Chinese Pharmaceutical Journal
; (24): 1843-1846, 2018.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-858166
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To establish an HPLC method for determination of ferulic acid in Ligusticum Wallichii,which is the active ingredient of Xinmaishu capsules.METHODS:
The content was determined by HPLC. The analysis was carried out on C18(4.6 mm×250 mm,5 μm) column. The mobile phase consisted of acetonitrile-0.3% acetic acid(13∶87). The flow rate was 1.0 mL·min-1, and the UV detection wavelength was set at 322 nm.RESULTS:
The linearity range of the calibration curve for ferulic acid was from 1.0 to 10.0 μg·mL-1 (r=0.999 8). The average recovery rate was 99.57% with RSD of 0.75%(n=9).CONCLUSION:
This method is sensitive, accurate,reproducible and simple. It can be used for the quality control of ferulic acid in Xinmaishu capsules.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmaceutical Journal
Ano de publicação:
2018
Tipo de documento:
Artigo