Risk Factors Study for Stroke in Patients with Type 2 Diabetes Based on CHIRA Database / 中国药学杂志

ABSTRACT

OBJECTIVE: To analyze the risk factors for stroke in patients with type 2 diabetes in China by using CHIRA database and control the expenditure of medicine for stroke patients and reducing the economic burden of medical insurance funds. METHODS: The data of T2DM patients in the 2015 CHIRA database were collected. The new stroke patients were used as a baseline group. The stroke-free patients who have the similar baseline were selected as the control group by using the PSM. At last, Logistic regression model was used to analyze the relationship between chronic complications of type 2 diabetes and stroke in T2DM patients. RESULTS: Four thousand four hundred and fifty patients were included after using the PSM. Two thousand one hunderd and forty-five(48.20%) patients were diagnosed with chronic complications and 1 138 patients were diagnosed with stroke (53.05%), higher than patietnts who have no chronic complications (47.16%, P<0.0001). Logistic regression model showed that cardiovascular complication(OR=1.19,95%CI1.05-1.34) and peripheral neuropathy (OR=1.34,95%CI1.11-1.62) are independent risk factors for stroke. CONCLUSION: Cardiovascular complication and peripheral neuropathy of patients with type 2 diabetes are independent risk factors for stroke.