The effect of phloretin on rBMECs uptake of ginsenoside Rb1 / 中国药学杂志
Chinese Pharmaceutical Journal
; (24): 226-232, 2015.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-859367
Biblioteca responsável:
WPRO
ABSTRACT
OBJECTIVE:
To evaluate the effect of phloretin on the uptake of ginsenoside Rb1 by the cell model, primary rat brain microvascular endothelial cells, (rBMEC) in vitro.METHODS:
Experiments were divided into two groups, ginsenoside Rb1 with and without the addition of phloretin intervention. The cellular uptake of ginsenoside Rb1 was determined by LC-MS/MS. Protein content in cultured cells was measured by the method of BCA.RESULTS:
The uptake amount of ginsenoside Rb1 in rBMEC with phloretin was significantly lower(P < 0.05).CONCLUSION:
The uptake of ginsenoside Rb1 by rBMEC is significantly inhibited by phloretin.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Chinês
Revista:
Chinese Pharmaceutical Journal
Ano de publicação:
2015
Tipo de documento:
Artigo