Progress of macrolide-resistant mycoplasma pneumoniae pneumonia in children / 国际儿科学杂志

ABSTRACT

Mycoplasma pneumoniae pneumonia is one of the common community-acquired pneumonia.Macrolides are the drugs of first choice for the treatment of mycoplasma pneumoniae pneumonia in children.The macrolide resistance in Asia is severe and has a rising trend year by year.The mechanism is mainly the 23S rRNA gene mutation.Children infected with drug-resistant strains are more likely to have clinical manifestations of severe pneumonia, and even acute respiratory distress syndrome.The increased resistance of mycoplasma pneumoniae is related to the high frequency and long application time of macrolides.This article reviews the research progress, status, mechanism, clinical manifestations and its relationship with macrolide-resistant mycoplasma pneumoniae pneumonia in children.