Progress on the effect and mechanism of formaldehyde on asthma in children / 国际儿科学杂志

ABSTRACT

In recent years, the prevalence of childhood asthma has been increasing globally.As a common indoor pollutant, formaldehyde is involved in the pathogenesis of asthma, which has drawn increasing attention.However, the results of the current research have not been unified.Some studies have shown that asthma children live in indoor environments where the concentration of formaldehyde is significantly higher than that of healthy children.There are also reports showing that formaldehyde is not an independent risk factor for asthma.The exact results need to be further studied with a larger sample size.In addition, the article concludes the possible mechanism of formaldehyde on asthma from the perspectives of airway inflammation, acquired allergies, and enzymology, providing new ideas for the prevention and treatment of asthma.