Progress of multidisciplinary treatment of intrahepatic cholangiocarcinoma / 国际外科学杂志

ABSTRACT

Intrahepatic cholangiocellular carcinoma (ICC) has become the second common malignant tumors of the liver,with its incidence being next only to hepatocellular carcinoma (HCC).Due to the lack of targeted screening methods and specific clinical manifestations,most intrahepatic cholangiocarcinoma (ICC) is clearly diagnosed as advanced,which brings great difficulties to the treatment of ICC.At present,radical surgical resection is still the most effective method to ICC.However,for some patients who had a positive-margin (R1) resection or positive lymph node metastasis,multidisciplinary comprehensive treatment including transcatheter arterial chemoembolization (TACE),local ablation,systemic chemotherapy,targeted therapy and immunotherapy,etc.can effectively improve the prognosis of these patients.