Mechanisms linking chronic obstructive pulmonary disease and sarcopenia / 中华老年医学杂志

ABSTRACT

Sarcopenia is a geriatric syndrome characterized by the decline in muscle mass and function associated with aging.Many studies have revealed that secondary sarcopenia associated with chronic obstructive pulmonary disease(COPD)can further reduce lung function and the ability of conducting daily living activities for the patients.Moreover, inflammation, increased energy expenditure, decreased physical endurance induced by COPD may accelerate the deterioration of sarcopenia.The aim of this review is to tentatively explore possible mechanisms linking the two diseases and promote early intervention for sarcopenia.