Prognostic influencing factors in patients of Barcelona stage B hepatocellular carcinoma undergoing hepatectomy / 中华普通外科杂志
Chinese Journal of General Surgery
; (12): 215-218, 2020.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-870436
Biblioteca responsável:
WPRO
ABSTRACT
Objective:
To investigate the prognostic factors that influence Barcelona (Barcelona clinical liver cancer staging system, BCLC)stage B hepatocellular carcinoma patients after hepatectomy.Methods:
Retrospective analysis was made on clinical and pathological data of 50 standardized hemihepatectomy in Barcelona stage B hepatocellular carcinoma from 2013 to 2017.Results:
Single-factor results showed that high expression of tumor microvascular invasion (MVI) and proliferation of nuclear antigen (Ki-67) were the prognostic factors ( respectively χ 2 =8.411, 10.939, all P<0.05). Multivariate analysis showed that the difference of high expression of Ki-67 and survival rate was statistically significant (respectively F=5.710, 8.254, all P<0.05). Ki-67 expression level and tumor differentiation were statistically significant (χ 2=0.497, P<0.05). There was a statistically significant difference in survival between the high-risk group and the low-risk group according to the risk factors (χ 2=12.152, P<0.05).Conclusions:
MVI and high expression of Ki-67 were high risk factors affecting the overall survival rate of liver cancer after hemihepatectomy.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Tipo de estudo:
Estudo prognóstico
/
Fatores de risco
Idioma:
Chinês
Revista:
Chinese Journal of General Surgery
Ano de publicação:
2020
Tipo de documento:
Artigo