Heterotopic Heart Transplantation in the Rat Model / 대한흉부외과학회지
The Korean Journal of Thoracic and Cardiovascular Surgery
; : 531-535, 1998.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-87224
Biblioteca responsável:
WPRO
ABSTRACT
In 1964, Abbott and Colleagues published the world's first heterotopic heart transplantation technique in the rat. Their method established circulation by end-to-end anastomoses of the graft's aorta and pulmonary artery to the recipient's abdominal aorta and Inferior Vena Cava (IVC), respectively. In 1966, Tomita et al altered Abbott's technique by employing end-to-side rather than end-to-end anastomoses, thus eliminating the hind leg paralysis that sometimes resulted from Abbott's technique. In order to prevent postsuture hemorrhage (since 7-0 silk suture was the finest available at that time), Tomita's aortic anastomosis was done with double up-and-down continuous suture technique. A single layer continuous anstomosis effected the pulmonary artery-IVC anastomosis. The availability of Nylon monofilament suture made it possible for Ono and Lindsey to use a single layer suture technique for the aortic end-to-side anastomosis in their modified rat heart transplantation. We observed survival time between control group and Immunosuppression (Cyclosporine administration, 10mg/Kgx4 times postoperatively) group after heterotopic heart transplantation in the rat model. The cyclosporine adminstration group survived longer than the control group, thus we concluded that cyclosporine was based on Immunosuppressive drugs.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Aorta
/
Aorta Abdominal
/
Paralisia
/
Artéria Pulmonar
/
Suturas
/
Veia Cava Inferior
/
Técnicas de Sutura
/
Transplante de Coração
/
Terapia de Imunossupressão
/
Ciclosporina
Limite:
Animais
Idioma:
Coreano
Revista:
The Korean Journal of Thoracic and Cardiovascular Surgery
Ano de publicação:
1998
Tipo de documento:
Artigo