Management of silicosis patients complicated with respiratory failure by mechanical ventilation with lung dilation and sputum suction / 中国职业医学

ABSTRACT

OBJECTIVE: To explore the curative effect of mechanical ventilation combined with lung dilation and sputum suction in silicosis patients complicated with respiratory failure. METHODS: By a random number table method,76 silicosis patients complicated with respiratory failure from 2013 to 2016 were selected as study subjects. They were divided into control group( 38 cases) and observation group( 38 cases). The control group was treated with routine sputum suction and artificial airway nursing; the observation group was treated with lung dilation and sputum suction based on the control group'nursing. After 1 week of treatment,airway resistance,oxygen partial pressure( PaO_2),blood oxygen saturation( SaO_2),incidence and mortality of ventilator associated pneumonia( VAP),and the incidence of atelectasis were compared between the two groups. RESULTS: There was no statistical significant difference found in airway resistance,PaO_2 and SaO_2 between the two groups of patients before treatment( P > 0. 05). The two groups of patients after treatment were compared with the same group before treatment,airway resistance decreased( P < 0. 01),PaO_2 and SaO_2 were increased( P < 0. 01). After treatment,the airway resistance of patients in observation group was lower than that of the control group( P < 0. 01),while PaO_2 and SaO_2 were higher than that in control group( P < 0. 01). Compared with control group,the incidence,mortality and pulmonary atelectasis rate of VAP in observation group were lower than that of control group( P < 0. 05). CONCLUSION: Treatment of patients with silicosis and respiratory failure by mechanical ventilation with lung dilation and sputum suction is helpful to reduce the incidence and mortality of VAP and improve treatment outcomes.