Predictive Biomarkers of Immune-related Adverse Events Induced by Checkpoint Inhibitors in Malignancies / 中国医学科学院学报
Acta Academiae Medicinae Sinicae
; (6): 825-830, 2020.
Artigo
em Chinês
| WPRIM (Pacífico Ocidental)
| ID: wpr-878685
Biblioteca responsável:
WPRO
ABSTRACT
While immune checkpoint inhibitors(ICIs)are effective and promising treatments for a variety of malignancies,they also have safety concerns,especially the immune-related adverse events(irAEs).Unlike the side effects of traditional chemotherapy and targeted therapy,irAEs are adverse events caused by immune activation after ICIs treatment and thus may involve almost every system of the body.Therefore,biomarkers for predicting irAEs after ICIs treatment are urgently needed.Here we review the currently available predictive biomarkers of irAEs.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Assunto principal:
Biomarcadores
/
Inibidores de Checkpoint Imunológico
/
Imunoterapia
/
Neoplasias
Tipo de estudo:
Estudo prognóstico
Limite:
Humanos
Idioma:
Chinês
Revista:
Acta Academiae Medicinae Sinicae
Ano de publicação:
2020
Tipo de documento:
Artigo