The research progress of DNA methylation in bladder cancer / 中华泌尿外科杂志
Chinese Journal of Urology
; (12): 312-315, 2021.
Article
em Zh
| WPRIM
| ID: wpr-885013
Biblioteca responsável:
WPRO
ABSTRACT
Bladder cancer is a malignant tumor of the urinary system with the highest and still increasing incidence rate in China in recent years. While most patients with a diagnosis of non-muscle invasive bladder cancer (NMIBC) have a good prognosis, NMIBC is prone to relapse and progress to muscular invasive cancer (MIBC) after treatment, leading to a poor prognosis. At present, diagnosis and postoperative follow-up of bladder cancer still rely on invasive cystoscopy, and there is a lack of effective treatment for advanced tumors. The results show that methylation, as a chemical modification of DNA, is related to the occurrence and development of bladder cancers. This article reviews the research progress of bladder cancer DNA methylation in diagnosis, monitoring and treatment in recent years.
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Base de dados:
WPRIM
Idioma:
Zh
Revista:
Chinese Journal of Urology
Ano de publicação:
2021
Tipo de documento:
Article