Inhibition of LIM kinase reduces contraction and proliferation in bladder smooth muscle
Acta Pharmaceutica Sinica B
; (6): 1914-1930, 2021.
Artigo
em Inglês
| WPRIM (Pacífico Ocidental)
| ID: wpr-888842
Biblioteca responsável:
WPRO
ABSTRACT
Overactive bladder (OAB) is the most bothersome symptom in lower urinary tract symptoms (LUTS). Current pharmacologic treatment aims to inhibit detrusor contraction; however, shows unsatisfied efficacy and high discontinuation rate. LIM kinases (LIMKs) promote smooth muscle contraction in the prostate; however, their function in the bladder smooth muscle remains unclear. Here, we studied effects of the LIMK inhibitors on bladder smooth muscle contraction and proliferation both
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Inglês
Revista:
Acta Pharmaceutica Sinica B
Ano de publicação:
2021
Tipo de documento:
Artigo