Urinary Extracellular Vesicles as Biomarkers of Kidney Disease / 대한내과학회지
Korean Journal of Medicine
; : 36-41, 2021.
Artigo
em Coreano
| WPRIM (Pacífico Ocidental)
| ID: wpr-902257
Biblioteca responsável:
WPRO
ABSTRACT
Extracellular vesicles (EVs) are membrane-bound vesicles produced and released into the extracellular fluid by cells under physiological and stressful conditions. They play a role as intracellular communicators by carrying and delivering biomolecules, such as proteins, lipids, or nucleic acids. Urinary EVs have gained important recognition as potential diagnostic biomarkers in renal disease, as they can originate from diverse cell types, including glomerular podocytes, tubular epithelial cells, or endothelial cells. Accumulating evidence has emphasized the feasibility of using EVs as biomarkers for diagnostic, prognostic, and therapeutic purposes in several forms of renal disease, such as acute kidney injury, glomerulonephritis, and renal transplantation. In this review, we introduce recent studies that attempt to identify urinary EVs as candidate biomarkers for human kidney diseases and consider their potential implications as a therapeutic option in significant kidney diseases.
Texto completo:
Disponível
Base de dados:
WPRIM (Pacífico Ocidental)
Idioma:
Coreano
Revista:
Korean Journal of Medicine
Ano de publicação:
2021
Tipo de documento:
Artigo